Blastocyst-endometrium interaction: intertwining a cytokine network
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چکیده
منابع مشابه
Blastocyst-endometrium interaction: intertwining a cytokine network.
The successful implantation of the blastocyst depends on adequate interactions between the embryo and the uterus. The development of the embryo begins with the fertilized ovum, a single totipotent cell which undergoes mitosis and gives rise to a multicellular structure named blastocyst. At the same time, increasing concentrations of ovarian steroid hormones initiate a complex signaling cascade ...
متن کاملI-34: Interactorme of Human Embryo Implan Implantation:Pathways,Networks
Background: A prerequisite for successful embryo implantation is adequate preparation of receptive endometrium and the establishment and maintenance of a viable embryo. The success of implantation further relies upon a two-way dialogue between the embryo and uterus. However, molecular bases of these preimplantation and implantation processes in humans are not well known. Materials and Methods: ...
متن کاملCytokine Profile in the Endometrium of Normal Fertile and Women with Repeated Implantation Failure
Background: Repeated Implantation Failure (RIF) is one of the most intricate obstacles in assisted reproduction. The cytokine and chemokine composition of uterine cavity seem to play important roles in the implantation process. Objective: To compare the cytokine profile in the endometrium of normal fertile women and those with repeated implantation failure. Methods: After enzymatic digestion of...
متن کاملThe role of interleukin on uterine endometrium, placenta and embryonic
Introduction: The polypeptide cytokine interleukin-1 is found in all body tissues and plays its role in inflammatory changes. Interleukin-1 is known as alarm cytokine in defense mechanism, particularly immunological responses. The interleukin receptor is present in different tissues and in endometrial epithelium and its antagonist will be increased during preimplantation period, therefore it ...
متن کاملDiscovery of candidate genes and pathways in the endometrium regulating ovine blastocyst growth and conceptus elongation.
Establishment of pregnancy in ruminants requires blastocyst growth to form an elongated conceptus that produces interferon tau, the pregnancy recognition signal, and initiates implantation. Blastocyst growth and development requires secretions from the uterine endometrium. An early increase in circulating concentrations of progesterone (P4) stimulates blastocyst growth and elongation in ruminan...
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ژورنال
عنوان ژورنال: Brazilian Journal of Medical and Biological Research
سال: 2006
ISSN: 0100-879X
DOI: 10.1590/s0100-879x2006005000023